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Foodtest - Mechanism of Food Allergy
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Mechanism of Food Allergy

 The mechanism of classical food allergy involves the release of inflammatory mediators after IgE antibodies bind to a mast cell.  The sequence of events is as follows:

 –     Food antigen stimulates a class of lymphocytes called Th2 helper T cells

 –     These Th2 helper T cells secrete cytokines that instruct B lymphocytes to produce antigen-specific IgE antibodies

 –    IgE antibodies bind to mast cells and stimulate the release of inflammatory mediators, including histamine

 –    Inflammation is caused, producing classical allergic symptoms such as sneezing, watery                                                          eyes, itching, rashes, difficulty breathing etc